Product Data Sheet

gGlu-2OMe SiR600

Catalog No. A44457

main product photo
gGlu-2OMe SiR600 is a γ-glutamyltranspeptidase (GGT) responsive fluorescent probe that enables lesion visualization through fluorescence activation. Upon interaction with GGT, this probe is converted into a highly fluorescent form, overcoming initial quenching via a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 is particularly effective in distinguishing malignant breast cancer from benign breast fibroadenoma tissues, making it a valuable tool for research in oncology and cancer diagnostics.
Chemical Information
Catalog NumA44457
M. Wt601.65
FormulaC29H30F3N3O6Si
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2730023-28-4
Synonyms
SMILESCOC1=C(C=CC=C1)C2=C3C=CC(C=C3[Si](C)(C4=CC(NC(CC[C@@H](C(O)=O)N)=O)=CC=C42)C)=N.FC(F)(F)C(O)=O
Biological Activity
DescriptiongGlu-2OMe SiR600 is a γ-glutamyltranspeptidase (GGT) responsive fluorescent probe that enables lesion visualization through fluorescence activation. Upon interaction with GGT, this probe is converted into a highly fluorescent form, overcoming initial quenching via a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 is particularly effective in distinguishing malignant breast cancer from benign breast fibroadenoma tissues, making it a valuable tool for research in oncology and cancer diagnostics.
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SHIPPING AND STORAGE
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