Product Data Sheet

4-MU-α-GlcNS sodium

Catalog No. A44514

main product photo
4-MU-α-GlcNS sodium is a fluorogenic substrate for heparin sulphamidase, which is desulfurized to produce 4-MU-α-GlcNH2. This metabolite is then hydrolyzed by α-glucosaminidase, resulting in the release of 4-methylumbelliferone (4-MU), a fluorescent compound with maximum emission wavelengths between 445-454 nm. 4-MU-α-GlcNS sodium is valuable in studying heparin sulphamidase deficiencies related to Mucopolysaccharidosis IIIA and other lysosomal disorders.
Chemical Information
Catalog NumA44514
M. Wt439.37
FormulaC16H18NNaO10S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.460085-45-4
Synonyms
SMILESO=S(N[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@H]1OC2=CC=C(C(C)=CC(O3)=O)C3=C2)(O[Na])=O
Biological Activity
Description4-MU-α-GlcNS sodium is a fluorogenic substrate for heparin sulphamidase, which is desulfurized to produce 4-MU-α-GlcNH2. This metabolite is then hydrolyzed by α-glucosaminidase, resulting in the release of 4-methylumbelliferone (4-MU), a fluorescent compound with maximum emission wavelengths between 445-454 nm. 4-MU-α-GlcNS sodium is valuable in studying heparin sulphamidase deficiencies related to Mucopolysaccharidosis IIIA and other lysosomal disorders.
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SHIPPING AND STORAGE
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