Product Data Sheet

IETDC

Catalog No. A44532

main product photo
IETDC is a specific substrate for caspase 8, designed to monitor its activity through a bioluminescent assay. Upon cleavage by activated caspase 8, IETDC releases D-cysteine, which subsequently interacts with HCBT to generate firefly luciferin, producing a detectable bioluminescent signal. This reagent is particularly valuable for investigating acute inflammation and understanding the role of caspase 8 in apoptotic signaling pathways.
Chemical Information
Catalog NumA44532
M. Wt741.81
FormulaC32H47N5O13S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1476735-95-1
Synonyms
SMILES
Biological Activity
DescriptionIETDC is a specific substrate for caspase 8, designed to monitor its activity through a bioluminescent assay. Upon cleavage by activated caspase 8, IETDC releases D-cysteine, which subsequently interacts with HCBT to generate firefly luciferin, producing a detectable bioluminescent signal. This reagent is particularly valuable for investigating acute inflammation and understanding the role of caspase 8 in apoptotic signaling pathways.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.