Product Data Sheet
Methoxy-X04
Catalog No. A44781
Methoxy-X04 is a fluorescent dye that selectively targets beta-pleated sheets associated with amyloid Aβ plaques, effectively crossing the blood-brain barrier. It exhibits a strong in vitro binding affinity for amyloid beta (Aβ) fibrils, with a Ki value of 26.8 nM. This compound is particularly valuable for visualizing plaques, tangles, and cerebrovascular amyloid in postmortem Alzheimer's disease brain sections, providing robust specificity for research applications in neurodegenerative disease studies.
Chemical Information
| Catalog Num | A44781 |
|---|---|
| M. Wt | 344.40 |
| Formula | C23H20O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 863918-78-9 |
| Synonyms | |
| SMILES | COC1=CC(/C=C/C2=CC=C(O)C=C2)=CC=C1/C=C/C3=CC=C(O)C=C3 |
Biological Activity
| Description | Methoxy-X04 is a fluorescent dye that selectively targets beta-pleated sheets associated with amyloid Aβ plaques, effectively crossing the blood-brain barrier. It exhibits a strong in vitro binding affinity for amyloid beta (Aβ) fibrils, with a Ki value of 26.8 nM. This compound is particularly valuable for visualizing plaques, tangles, and cerebrovascular amyloid in postmortem Alzheimer's disease brain sections, providing robust specificity for research applications in neurodegenerative disease studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
