Product Data Sheet
CO probe 1
Catalog No. A44836
CO Probe 1 is a highly effective fluorescent carbon monoxide (CO) probe designed for real-time imaging applications. It operates by utilizing the Tsuji-Trost reaction, where CO reduces Pd2+ to Pd0 in the presence of PdCl₂, resulting in the removal of the allyl protecting group and subsequent release of fluorescein. This process allows for a significant fluorescence enhancement of up to 150 times within 20 minutes, exhibiting high selectivity and rapid response with minimal cytotoxicity. CO Probe 1 is particularly valuable for investigating pathological mechanisms associated with CO signaling regulation in conditions such as inflammation, vascular disease, and cancer.
Chemical Information
| Catalog Num | A44836 |
|---|---|
| M. Wt | 481.32 |
| Formula | C26H18Cl2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1043865-37-7 |
| Synonyms | |
| SMILES | O=C1OC2(C3=CC(Cl)=C(C=C3OC4=CC(OCC=C)=C(C=C42)Cl)OCC=C)C5=C1C=CC=C5 |
Biological Activity
| Description | CO Probe 1 is a highly effective fluorescent carbon monoxide (CO) probe designed for real-time imaging applications. It operates by utilizing the Tsuji-Trost reaction, where CO reduces Pd2+ to Pd0 in the presence of PdCl₂, resulting in the removal of the allyl protecting group and subsequent release of fluorescein. This process allows for a significant fluorescence enhancement of up to 150 times within 20 minutes, exhibiting high selectivity and rapid response with minimal cytotoxicity. CO Probe 1 is particularly valuable for investigating pathological mechanisms associated with CO signaling regulation in conditions such as inflammation, vascular disease, and cancer. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
