6FC-GABA-Taxol
Catalog No. A45176

6FC-GABA-Taxol is a fluorescent probe designed for imaging microtubules in living cells. This compound is formed by conjugating 6-fluorescein carboxylic acid (6FC) to the anticancer agent Taxol through γ-aminobutyric acid (GABA), allowing effective binding to microtubules. 6FC-GABA-Taxol facilitates high-resolution imaging via confocal microscopy and allows for microtubule quantification using flow cytometry without requiring efflux inhibitors, making it a valuable tool for cancer research and cellular dynamics studies.
Chemical Information
| Catalog Num | A45176 |
|---|---|
| M. Wt | 1145.14 |
| Formula | C61H61FN2O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3055969-34-8 |
| Synonyms | |
| SMILES | O=C(N[C@@H](C1=CC=CC=C1)[C@@H](O)C(O[C@@H]2C(C)=C([C@@H](OC(C)=O)C([C@@]3(C)[C@]([C@](OC(C)=O)(CO4)[C@H]4C[C@@H]3OC(CCCNC(C5=CC6=CC(F)=C(O)C=C6OC5=O)=O)=O)([H])[C@@H]7OC(C8=CC=CC=C8)=O)=O)C(C)(C)[C@@]7(O)C2)=O)C9=CC=CC=C9 |
Biological Activity
| Description | 6FC-GABA-Taxol is a fluorescent probe designed for imaging microtubules in living cells. This compound is formed by conjugating 6-fluorescein carboxylic acid (6FC) to the anticancer agent Taxol through γ-aminobutyric acid (GABA), allowing effective binding to microtubules. 6FC-GABA-Taxol facilitates high-resolution imaging via confocal microscopy and allows for microtubule quantification using flow cytometry without requiring efflux inhibitors, making it a valuable tool for cancer research and cellular dynamics studies. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


