Product Data Sheet
Dabcyl-YVADAPV-EDANS
Catalog No. A45386
Dabcyl-YVADAPV-EDANS is a fluorogenic substrate specifically designed for the interleukin-1β converting enzyme (ICE) to monitor ICE-like protease activity. It exhibits fluorescence upon cleavage, with excitation at 360 nm and emission at 480 nm, facilitating sensitive detection. This substrate is instrumental in studying K+ deprivation-induced apoptosis in cerebellar granule neurons, making it a valuable tool for apoptosis and protease research.
Chemical Information
| Catalog Num | A45386 |
|---|---|
| M. Wt | 1233.39 |
| Formula | C61H76N12O14S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 161877-70-9 |
| Synonyms | |
| SMILES | S(=O)(=O)(O)C=1C2=C(C(NCCNC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC(=O)C5=CC=C(N=NC6=CC=C(N(C)C)C=C6)C=C5)=O)[C@H](C)C)=O)C)=O)CC(O)=O)=O)C)=O)CCC3)[C@@H](C)C)=O)=CC=C2)C=CC1 |
Biological Activity
| Description | Dabcyl-YVADAPV-EDANS is a fluorogenic substrate specifically designed for the interleukin-1β converting enzyme (ICE) to monitor ICE-like protease activity. It exhibits fluorescence upon cleavage, with excitation at 360 nm and emission at 480 nm, facilitating sensitive detection. This substrate is instrumental in studying K+ deprivation-induced apoptosis in cerebellar granule neurons, making it a valuable tool for apoptosis and protease research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
