Product Data Sheet
DCDAPH
Catalog No. A45419
DCDAPH is a specialized near-infrared fluorescent (NIRF) probe designed for the detection of β-amyloid (Aβ) plaques, with excitation and emission wavelengths of 597 nm and 665 nm, respectively, in phosphate-buffered saline. This compound demonstrates a notably high affinity for Aβ aggregates, with a dissociation constant (Kd) of 27 nM and an inhibition constant (Ki) of 37 nM. DCDAPH is capable of effectively permeating the blood-brain barrier, making it suitable for both in vitro and in vivo studies in Alzheimer's disease research.
Chemical Information
| Catalog Num | A45419 |
|---|---|
| M. Wt | 249.31 |
| Formula | C16H15N3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 125113-96-4 |
| Synonyms | |
| SMILES | CN(C1=CC=C(/C=C/C=C/C=C(C#N)/C#N)C=C1)C |
Biological Activity
| Description | DCDAPH is a specialized near-infrared fluorescent (NIRF) probe designed for the detection of β-amyloid (Aβ) plaques, with excitation and emission wavelengths of 597 nm and 665 nm, respectively, in phosphate-buffered saline. This compound demonstrates a notably high affinity for Aβ aggregates, with a dissociation constant (Kd) of 27 nM and an inhibition constant (Ki) of 37 nM. DCDAPH is capable of effectively permeating the blood-brain barrier, making it suitable for both in vitro and in vivo studies in Alzheimer's disease research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
