Product Data Sheet

SB 204741

Catalog No. A45819

main product photo
SB 204741 is a selective high-affinity antagonist of the 5-HT2B receptor, exhibiting a pKi value of 7.1. This compound is utilized in research exploring the role of 5-HT2B in various physiological and pathological processes. Its antagonistic properties make it valuable for studies on cardiac function, pulmonary effects, and potential therapeutic interventions in diseases related to serotonergic dysregulation.
Chemical Information
Catalog NumA45819
M. Wt286.35
FormulaC14H14N4OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.152239-46-8
Synonyms
SMILESO=C(NC1=CC(C)=NS1)NC2=CC3=C(N(C)C=C3)C=C2
Biological Activity
DescriptionSB 204741 is a selective high-affinity antagonist of the 5-HT2B receptor, exhibiting a pKi value of 7.1. This compound is utilized in research exploring the role of 5-HT2B in various physiological and pathological processes. Its antagonistic properties make it valuable for studies on cardiac function, pulmonary effects, and potential therapeutic interventions in diseases related to serotonergic dysregulation.
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