Product Data Sheet
Opiranserin hydrochloride
Catalog No. A45871
Opiranserin hydrochloride is a dual antagonist targeting glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), exhibiting IC50 values of 0.86 and 1.3 μM, respectively. In addition, it demonstrates antagonistic activity on recombinant P2X3 receptors with an IC50 of 0.87 μM. This compound is under development as an injectable analgesic for postoperative pain management, making it relevant for research in pain pathways and therapeutic interventions.
Chemical Information
| Catalog Num | A45871 |
|---|---|
| M. Wt | 430.97 |
| Formula | C21H35ClN2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1440796-75-7 |
| Synonyms | VVZ-149 hydrochloride |
| SMILES | O=C(C1=CC(OC)=C(OCCCC)C(OC)=C1)NCC2(CCOCC2)N(C)C.[H]Cl |
Biological Activity
| Description | Opiranserin hydrochloride is a dual antagonist targeting glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), exhibiting IC50 values of 0.86 and 1.3 μM, respectively. In addition, it demonstrates antagonistic activity on recombinant P2X3 receptors with an IC50 of 0.87 μM. This compound is under development as an injectable analgesic for postoperative pain management, making it relevant for research in pain pathways and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
