Product Data Sheet
SB-216641A
Catalog No. A45880
SB-216641A is a selective antagonist of the 5-HT1B and 5-HT1D receptors. This compound exhibits high affinity and specificity for the human 5-HT1B receptor while demonstrating minimal activity at the 5-HT1D receptor. SB-216641A is utilized in research applications aimed at understanding serotonergic signaling and the modulation of neuropsychological disorders. Additionally, it has been shown to inhibit the function of SKF-99101H, providing insights into receptor interactions and pharmacological effects.
Chemical Information
| Catalog Num | A45880 |
|---|---|
| M. Wt | 523.02 |
| Formula | C28H31ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 193611-67-5 |
| Synonyms | SB-216641 hydrochloride |
| SMILES | O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC.Cl |
Biological Activity
| Description | SB-216641A is a selective antagonist of the 5-HT1B and 5-HT1D receptors. This compound exhibits high affinity and specificity for the human 5-HT1B receptor while demonstrating minimal activity at the 5-HT1D receptor. SB-216641A is utilized in research applications aimed at understanding serotonergic signaling and the modulation of neuropsychological disorders. Additionally, it has been shown to inhibit the function of SKF-99101H, providing insights into receptor interactions and pharmacological effects. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
