Product Data Sheet
Frovatriptan succinate hydrate
Catalog No. A45884
Frovatriptan succinate hydrate is a selective agonist for the 5-HT1B and 5-HT1D receptors, exhibiting a pK50 value of 8.2. It demonstrates over 10-fold selectivity for these serotonin receptors compared to 5-HT1A, 5-HT1F, and 5-HT7, and exhibits greater than 1000-fold selectivity over other serotonin, dopamine, histamine H1, and α1-adrenoceptors. This compound is valuable for research into migraine pathophysiology and therapeutic applications.
Chemical Information
| Catalog Num | A45884 |
|---|---|
| M. Wt | 379.41 |
| Formula | C18H25N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 158930-17-7 |
| Synonyms | (R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate |
| SMILES | O=C(O)CCC(O)=O.O=C(C1=CC2=C(NC3=C2C[C@H](NC)CC3)C=C1)N.O |
Biological Activity
| Description | Frovatriptan succinate hydrate is a selective agonist for the 5-HT1B and 5-HT1D receptors, exhibiting a pK50 value of 8.2. It demonstrates over 10-fold selectivity for these serotonin receptors compared to 5-HT1A, 5-HT1F, and 5-HT7, and exhibits greater than 1000-fold selectivity over other serotonin, dopamine, histamine H1, and α1-adrenoceptors. This compound is valuable for research into migraine pathophysiology and therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
