Product Data Sheet
LY-272015 hydrochloride
Catalog No. A45892
LY-272015 hydrochloride is a specific antagonist of the 5-HT2B receptor. It effectively inhibits ERK2 phosphorylation triggered by serotonin (5-HT) or BW723C86, highlighting its role in modulating signaling pathways associated with serotonin receptors. Additionally, this compound demonstrates antihypertensive properties in models of DOCA-salt-induced hypertension, making it a valuable tool for research in cardiovascular and neuropharmacological studies.
Chemical Information
| Catalog Num | A45892 |
|---|---|
| M. Wt | 372.89 |
| Formula | C21H25ClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 172895-15-7 |
| Synonyms | |
| SMILES | CC1=CC2=C(NC3=C2CCNC3CC4=CC=C(OC)C(OC)=C4)C=C1.[H]Cl |
Biological Activity
| Description | LY-272015 hydrochloride is a specific antagonist of the 5-HT2B receptor. It effectively inhibits ERK2 phosphorylation triggered by serotonin (5-HT) or BW723C86, highlighting its role in modulating signaling pathways associated with serotonin receptors. Additionally, this compound demonstrates antihypertensive properties in models of DOCA-salt-induced hypertension, making it a valuable tool for research in cardiovascular and neuropharmacological studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
