Product Data Sheet
SB-200646A
Catalog No. A45905
SB-200646A is a selective antagonist of the 5-HT2B and 5-HT2C receptors, exhibiting pKi values of 7.5 for 5-HT2B, 6.9 for 5-HT2C, and 5.2 for 5-HT2A, highlighting its specificity. This compound is orally active and demonstrates significant electrophysiological and anxiolytic effects in vivo, making it a valuable tool for research in neuropharmacology and the study of serotonin receptor-mediated pathways.
Chemical Information
| Catalog Num | A45905 |
|---|---|
| M. Wt | 302.76 |
| Formula | C15H15ClN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 143797-62-0 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CN=C1)NC2=CC3=C(N(C)C=C3)C=C2.[H]Cl |
Biological Activity
| Description | SB-200646A is a selective antagonist of the 5-HT2B and 5-HT2C receptors, exhibiting pKi values of 7.5 for 5-HT2B, 6.9 for 5-HT2C, and 5.2 for 5-HT2A, highlighting its specificity. This compound is orally active and demonstrates significant electrophysiological and anxiolytic effects in vivo, making it a valuable tool for research in neuropharmacology and the study of serotonin receptor-mediated pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
