Product Data Sheet
(E)-3,4,5-Trimethoxycinnamic acid
Catalog No. A45924
(E)-3,4,5-Trimethoxycinnamic acid is a potent GABAA/BZ receptor agonist characterized by multiple methoxy substitutions on its cinnamic acid structure. This compound demonstrates significant biological activity, including anticonvulsant and sedative effects, making it a valuable tool in research related to insomnia, headaches, and epilepsy. Additionally, (E)-3,4,5-Trimethoxycinnamic acid exhibits favorable binding affinity to the 5-HT2C and 5-HT1A receptors, with IC50 values of 2.5 and 7.6 μM, respectively, supporting its potential in neuropharmacological studies.
Chemical Information
| Catalog Num | A45924 |
|---|---|
| M. Wt | 238.24 |
| Formula | C12H14O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 20329-98-0 |
| Synonyms | TMCA |
| SMILES | O=C(O)/C=C/C1=CC(OC)=C(OC)C(OC)=C1 |
Biological Activity
| Description | (E)-3,4,5-Trimethoxycinnamic acid is a potent GABAA/BZ receptor agonist characterized by multiple methoxy substitutions on its cinnamic acid structure. This compound demonstrates significant biological activity, including anticonvulsant and sedative effects, making it a valuable tool in research related to insomnia, headaches, and epilepsy. Additionally, (E)-3,4,5-Trimethoxycinnamic acid exhibits favorable binding affinity to the 5-HT2C and 5-HT1A receptors, with IC50 values of 2.5 and 7.6 μM, respectively, supporting its potential in neuropharmacological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
