Product Data Sheet
Roemerine
Catalog No. A45925
Roemerine is an alkaloid derived from the leaves of Fibraurea recisa Pierre, acting primarily as an endogenous metabolite. It demonstrates antibacterial, anticancer, and antidepressant activities, with mechanisms including reversal of multidrug resistance in cultured cells and modulation of the cAMP signaling pathway. Additionally, Roemerine enhances neuronal activity by increasing brain-derived neurotrophic factor (BDNF) protein expression and influencing serotonergic and glutamatergic systems. This compound is valuable for research applications in cancer, infectious diseases, and neurological disorders.
Chemical Information
| Catalog Num | A45925 |
|---|---|
| M. Wt | 279.33 |
| Formula | C18H17NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 548-08-3 |
| Synonyms | (-)-Roemerine |
| SMILES | CN1CCC(C2=C3C4=CC=CC=C4C[C@@]12[H])=CC5=C3OCO5 |
Biological Activity
| Description | Roemerine is an alkaloid derived from the leaves of Fibraurea recisa Pierre, acting primarily as an endogenous metabolite. It demonstrates antibacterial, anticancer, and antidepressant activities, with mechanisms including reversal of multidrug resistance in cultured cells and modulation of the cAMP signaling pathway. Additionally, Roemerine enhances neuronal activity by increasing brain-derived neurotrophic factor (BDNF) protein expression and influencing serotonergic and glutamatergic systems. This compound is valuable for research applications in cancer, infectious diseases, and neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
