Product Data Sheet
Eplivanserin hemifumarate
Catalog No. A45930
Eplivanserin hemifumarate is a potent and selective antagonist of the 5-HT2A receptor, exhibiting an IC50 of 5.8 nM in rat cortical membranes and a Kd of 1.14 nM. It demonstrates greater than 20-fold selectivity for the 5-HT2A subtype over 5-HT2B and 5-HT2C receptors. This compound is valuable for research focused on neuropharmacology and the modulation of serotonergic pathways in various biological processes.
Chemical Information
| Catalog Num | A45930 |
|---|---|
| M. Wt | 386.43 |
| Formula | C19H21FN2O2.1/2C4H4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 130580-02-8 |
| Synonyms | SR-46349 hemifumarate; SR 46349B |
| SMILES | O=C(O)/C=C/C(O)=O.OC(C=C1)=CC=C1/C=C/C(C2=C(C=CC=C2)F)=N/OCCN(C)C.[1/2] |
Biological Activity
| Description | Eplivanserin hemifumarate is a potent and selective antagonist of the 5-HT2A receptor, exhibiting an IC50 of 5.8 nM in rat cortical membranes and a Kd of 1.14 nM. It demonstrates greater than 20-fold selectivity for the 5-HT2A subtype over 5-HT2B and 5-HT2C receptors. This compound is valuable for research focused on neuropharmacology and the modulation of serotonergic pathways in various biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
