Product Data Sheet
Cinanserin hydrochloride
Catalog No. A45932
Cinanserin hydrochloride is a potent and selective antagonist of the 5-HT2 receptor, exhibiting a binding affinity with a Ki of 41 nM. This compound demonstrates a much higher selectivity for the 5-HT2 receptor compared to the 5-HT1 receptor, which has a Ki value of 3500 nM. Additionally, Cinanserin hydrochloride inhibits the 3C-like proteinase of the severe acute respiratory syndrome coronavirus, effectively reducing viral replication in vitro. This dual functionality makes it a valuable tool for research in neuropharmacology and virology.
Chemical Information
| Catalog Num | A45932 |
|---|---|
| M. Wt | 376.94 |
| Formula | C20H25ClN2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 54-84-2 |
| Synonyms | SQ 10643 |
| SMILES | O=C(NC1=CC=CC=C1SCCCN(C)C)/C=C/C2=CC=CC=C2.[H]Cl |
Biological Activity
| Description | Cinanserin hydrochloride is a potent and selective antagonist of the 5-HT2 receptor, exhibiting a binding affinity with a Ki of 41 nM. This compound demonstrates a much higher selectivity for the 5-HT2 receptor compared to the 5-HT1 receptor, which has a Ki value of 3500 nM. Additionally, Cinanserin hydrochloride inhibits the 3C-like proteinase of the severe acute respiratory syndrome coronavirus, effectively reducing viral replication in vitro. This dual functionality makes it a valuable tool for research in neuropharmacology and virology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
