Product Data Sheet
Velusetrag hydrochloride
Catalog No. A45942
Velusetrag hydrochloride is a selective agonist of the serotonin 5-HT4 receptor (5-HT4R) with a reported pKi of 7.7, demonstrating potent activity in modulating serotonin pathways. This compound shows negligible affinity for 5-HT2A and 5-HT2B receptors (Ki > 10 μM), making it suitable for specific therapeutic investigations. Velusetrag hydrochloride is particularly relevant for research into gastrointestinal disorders and Parkinson's disease, contributing to the understanding and potential treatment of these conditions.
Chemical Information
| Catalog Num | A45942 |
|---|---|
| M. Wt | 541.10 |
| Formula | C25H37ClN4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 866933-51-9 |
| Synonyms | TD-5108 hydrochloride |
| SMILES | [H]Cl.O=C(C1=CC2=C(N(C(C)C)C1=O)C=CC=C2)N[C@@H]3C[C@@H](N4C[C@@H](O)CN(C)S(=O)(C)=O)CC[C@@H]4C3 |
Biological Activity
| Description | Velusetrag hydrochloride is a selective agonist of the serotonin 5-HT4 receptor (5-HT4R) with a reported pKi of 7.7, demonstrating potent activity in modulating serotonin pathways. This compound shows negligible affinity for 5-HT2A and 5-HT2B receptors (Ki > 10 μM), making it suitable for specific therapeutic investigations. Velusetrag hydrochloride is particularly relevant for research into gastrointestinal disorders and Parkinson's disease, contributing to the understanding and potential treatment of these conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
