Product Data Sheet
Quipazine dimaleate
Catalog No. A45962
Quipazine dimaleate is a potent 5-HT agonist, demonstrating a Ki value of 1.4 nM for displacing [3H]GR65630 from the 5-HT3 receptor in rat models. This compound exhibits antiviral activity against SARS-CoV-2, with an EC50 of 31.64 μM, and acts as a 5-HT3 receptor antagonist in peripheral models. Quipazine dimaleate is valuable for research in neurological diseases, providing insights into serotonin receptor modulation and antiviral mechanisms.
Chemical Information
| Catalog Num | A45962 |
|---|---|
| M. Wt | 445.42 |
| Formula | C21H23N3O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 150323-78-7 |
| Synonyms | |
| SMILES | O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O.C1(N2CCNCC2)=NC3=CC=CC=C3C=C1 |
Biological Activity
| Description | Quipazine dimaleate is a potent 5-HT agonist, demonstrating a Ki value of 1.4 nM for displacing [3H]GR65630 from the 5-HT3 receptor in rat models. This compound exhibits antiviral activity against SARS-CoV-2, with an EC50 of 31.64 μM, and acts as a 5-HT3 receptor antagonist in peripheral models. Quipazine dimaleate is valuable for research in neurological diseases, providing insights into serotonin receptor modulation and antiviral mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
