Product Data Sheet
LY266097 hydrochloride
Catalog No. A45964
LY266097 hydrochloride is a selective antagonist of the 5-HT2B receptor, with pKis of 7.7, 9.8, and 7.6 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. The blockade of the 5-HT2B receptor by LY266097 is significant for investigating pathways associated with depression and other neuropsychiatric disorders. This compound provides valuable insights into serotonergic signaling and may aid in the development of therapeutic strategies targeting these receptors.
Chemical Information
| Catalog Num | A45964 |
|---|---|
| M. Wt | 407.33 |
| Formula | C21H24Cl2N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 172895-39-5 |
| Synonyms | |
| SMILES | CC1=CC2=C(NC3=C2CCNC3CC4=CC=C(OC)C(OC)=C4Cl)C=C1.[H]Cl |
Biological Activity
| Description | LY266097 hydrochloride is a selective antagonist of the 5-HT2B receptor, with pKis of 7.7, 9.8, and 7.6 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. The blockade of the 5-HT2B receptor by LY266097 is significant for investigating pathways associated with depression and other neuropsychiatric disorders. This compound provides valuable insights into serotonergic signaling and may aid in the development of therapeutic strategies targeting these receptors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
