Alniditan dihydrochloride
Catalog No. A45965

Alniditan dihydrochloride is a selective agonist of the 5-HT1B and 5-HT1D receptors, exhibiting IC50 values of 1.7 nM and 1.3 nM, respectively, in HEK293 cells. This compound demonstrates significant efficacy in preventing migraines, making it a valuable tool in migraine research. Its potent action on serotonin receptors highlights its potential applications in the study of headache disorders and related therapeutics.
Chemical Information
| Catalog Num | A45965 |
|---|---|
| M. Wt | 375.34 |
| Formula | C17H28Cl2N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 155428-00-5 |
| Synonyms | Alnitidan dihydrochloride |
| SMILES | [H]Cl.[H]Cl.C1(NCCCNC[C@H]2CCC3=CC=CC=C3O2)=NCCCN1 |
Biological Activity
| Description | Alniditan dihydrochloride is a selective agonist of the 5-HT1B and 5-HT1D receptors, exhibiting IC50 values of 1.7 nM and 1.3 nM, respectively, in HEK293 cells. This compound demonstrates significant efficacy in preventing migraines, making it a valuable tool in migraine research. Its potent action on serotonin receptors highlights its potential applications in the study of headache disorders and related therapeutics. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


