Product Data Sheet
MT-1207
Catalog No. A45970
MT-1207 is a highly selective antagonist of the adrenergic α1 and 5-HT2A receptors, demonstrating remarkable potency with IC50 values of <0.1 nM for α1A, 0.15 nM for α1B, 1.40 nM for α1D, and 0.27 nM for 5-HT2A. This compound effectively reduces blood pressure in the 2K2C rat model, preserving renal function. MT-1207 is a promising candidate for research into vasodilatation and related cardiovascular therapies.
Chemical Information
| Catalog Num | A45970 |
|---|---|
| M. Wt | 428.98 |
| Formula | C21H25ClN6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1610794-70-1 |
| Synonyms | |
| SMILES | C1(SN=C2N3CCN(CCCCN4N=NC5=C4C=CC=C5)CC3)=C2C=CC=C1.Cl |
Biological Activity
| Description | MT-1207 is a highly selective antagonist of the adrenergic α1 and 5-HT2A receptors, demonstrating remarkable potency with IC50 values of <0.1 nM for α1A, 0.15 nM for α1B, 1.40 nM for α1D, and 0.27 nM for 5-HT2A. This compound effectively reduces blood pressure in the 2K2C rat model, preserving renal function. MT-1207 is a promising candidate for research into vasodilatation and related cardiovascular therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
