Product Data Sheet
BIMU 8
Catalog No. A46024
BIMU 8 is a highly selective agonist of the 5-HT4 receptor, demonstrating EC50 values of 18 nM for the wild type receptor, 77 nM for the T3.36A mutant, and 540 nM for the W6.48A mutant. This compound facilitates research into serotonin signaling pathways and may have applications in studying gastrointestinal motility and cognitive disorders related to the 5-HT4 receptor. Scientists can leverage BIMU 8's potency and selectivity for detailed pharmacological investigations.
Chemical Information
| Catalog Num | A46024 |
|---|---|
| M. Wt | 377.89 |
| Formula | C19H26ClN4O2- |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 134296-40-5 |
| Synonyms | |
| SMILES | CN([C@@H](CC1)C2)[C@H]1C[C@@H]2NC(N3C4=C(C=CC=C4)N(C(C)C)C3=O)=O.[Cl-] |
Biological Activity
| Description | BIMU 8 is a highly selective agonist of the 5-HT4 receptor, demonstrating EC50 values of 18 nM for the wild type receptor, 77 nM for the T3.36A mutant, and 540 nM for the W6.48A mutant. This compound facilitates research into serotonin signaling pathways and may have applications in studying gastrointestinal motility and cognitive disorders related to the 5-HT4 receptor. Scientists can leverage BIMU 8's potency and selectivity for detailed pharmacological investigations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
