Product Data Sheet

RS 39604

Catalog No. A46027

main product photo
RS 39604 is a potent and selective antagonist of the 5-HT4 receptor, exhibiting a pKi of 9.1 in guinea pig striatal membranes. It demonstrates minimal affinity for other serotonin receptors, including 5-HT1A, 5-HT2C, and 5-HT3, as well as for various adrenergic, dopaminergic, muscarinic, angiotensin, and opioid receptors. RS 39604's distinctive profile makes it a valuable tool in research focusing on gastrointestinal motility disorders and neuropharmacology.
Chemical Information
Catalog NumA46027
M. Wt590.56
FormulaC26H37Cl2N3O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.167710-87-4
Synonyms
SMILESCS(=O)(NCCN1CCC(CCC(C2=CC(Cl)=C(N)C=C2OCC3=CC(OC)=CC(OC)=C3)=O)CC1)=O.Cl
Biological Activity
DescriptionRS 39604 is a potent and selective antagonist of the 5-HT4 receptor, exhibiting a pKi of 9.1 in guinea pig striatal membranes. It demonstrates minimal affinity for other serotonin receptors, including 5-HT1A, 5-HT2C, and 5-HT3, as well as for various adrenergic, dopaminergic, muscarinic, angiotensin, and opioid receptors. RS 39604's distinctive profile makes it a valuable tool in research focusing on gastrointestinal motility disorders and neuropharmacology.
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SHIPPING AND STORAGE
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