Product Data Sheet
SB 243213 dihydrochloride
Catalog No. A46031
SB 243213 dihydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. This compound displays over 100-fold selectivity for the 5-HT2C receptor relative to various neurotransmitter receptors, enzymes, and ion channels. SB 243213 dihydrochloride is noted for its improved anxiolytic profile and holds potential for therapeutic applications in schizophrenia and motor disorders.
Chemical Information
| Catalog Num | A46031 |
|---|---|
| M. Wt | 501.33 |
| Formula | C22H21Cl2F3N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1780372-25-9 |
| Synonyms | |
| SMILES | O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl.[H]Cl |
Biological Activity
| Description | SB 243213 dihydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. This compound displays over 100-fold selectivity for the 5-HT2C receptor relative to various neurotransmitter receptors, enzymes, and ion channels. SB 243213 dihydrochloride is noted for its improved anxiolytic profile and holds potential for therapeutic applications in schizophrenia and motor disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
