Product Data Sheet
Capeserod
Catalog No. A46033
Capeserod is a potent agonist of the serotonin 5-HT4 receptor, exhibiting a Ki of 0.6 nM. It is known to enhance the expression of key proteins such as phosphorylated cAMP-response element binding protein (p-CREB), vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), and B cell lymphoma-2 (Bcl-2) in the hippocampus. Capeserod demonstrates potential antidepressant-like efficacy in Wistar rat models, making it a valuable tool for research in neuropsychiatric disorders and serotonin signaling pathways.
Chemical Information
| Catalog Num | A46033 |
|---|---|
| M. Wt | 456.92 |
| Formula | C23H25ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 769901-96-4 |
| Synonyms | SL65.0155 free base |
| SMILES | O=C1OC(C2=C3OCCOC3=C(N)C(Cl)=C2)=NN1C4CCN(CC4)CCC5=CC=CC=C5 |
Biological Activity
| Description | Capeserod is a potent agonist of the serotonin 5-HT4 receptor, exhibiting a Ki of 0.6 nM. It is known to enhance the expression of key proteins such as phosphorylated cAMP-response element binding protein (p-CREB), vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), and B cell lymphoma-2 (Bcl-2) in the hippocampus. Capeserod demonstrates potential antidepressant-like efficacy in Wistar rat models, making it a valuable tool for research in neuropsychiatric disorders and serotonin signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
