Product Data Sheet

Fabesetron (FK1052 free base)

Catalog No. A46036

main product photo
Fabesetron is an orally active antagonist of both the 5-HT3 and 5-HT4 receptors. It exhibits significant biological activity in mitigating both acute and delayed emesis associated with cancer chemotherapy. This compound is valuable for research applications focusing on antiemetic therapies and the modulation of serotonin receptors in gastrointestinal motility.
Chemical Information
Catalog NumA46036
M. Wt293.36
FormulaC18H19N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129300-27-2
SynonymsFK1052 free base
SMILESO=C1N2C3=C(C=CC=C3)C(C)=C2CC[C@@H]1CC4=C(NC=N4)C
Biological Activity
DescriptionFabesetron is an orally active antagonist of both the 5-HT3 and 5-HT4 receptors. It exhibits significant biological activity in mitigating both acute and delayed emesis associated with cancer chemotherapy. This compound is valuable for research applications focusing on antiemetic therapies and the modulation of serotonin receptors in gastrointestinal motility.
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SHIPPING AND STORAGE
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