Product Data Sheet
SB 243213 hydrochloride
Catalog No. A46054
SB 243213 hydrochloride is a selective antagonist of the 5-HT2C receptor with high affinity, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human receptor. This compound demonstrates over 100-fold selectivity for the 5-HT2C receptor compared to various neurotransmitter receptors, enzymes, and ion channels. Its anxiolytic properties indicate potential applications in research related to schizophrenia and motor disorders.
Chemical Information
| Catalog Num | A46054 |
|---|---|
| M. Wt | 464.87 |
| Formula | C22H20ClF3N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 200940-23-4 |
| Synonyms | |
| SMILES | O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl |
Biological Activity
| Description | SB 243213 hydrochloride is a selective antagonist of the 5-HT2C receptor with high affinity, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human receptor. This compound demonstrates over 100-fold selectivity for the 5-HT2C receptor compared to various neurotransmitter receptors, enzymes, and ion channels. Its anxiolytic properties indicate potential applications in research related to schizophrenia and motor disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
