Product Data Sheet
OPC-14523 free base
Catalog No. A46061
OPC-14523 free base is a potent sigma and 5-HT1A receptor agonist. With a high affinity for sigma receptors (σ1/2 IC50=47/56 nM) and the 5-HT1A receptor (IC50=2.3 nM), along with activity at the 5-HT transporter (IC50=80 nM), it exhibits significant antidepressant-like effects. This compound is valuable for research applications investigating mood disorders and serotonergic signaling pathways.
Chemical Information
| Catalog Num | A46061 |
|---|---|
| M. Wt | 413.94 |
| Formula | C23H28ClN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 145969-30-8 |
| Synonyms | |
| SMILES | O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)C4=C(C(OC)=CC=C4)CC1 |
Biological Activity
| Description | OPC-14523 free base is a potent sigma and 5-HT1A receptor agonist. With a high affinity for sigma receptors (σ1/2 IC50=47/56 nM) and the 5-HT1A receptor (IC50=2.3 nM), along with activity at the 5-HT transporter (IC50=80 nM), it exhibits significant antidepressant-like effects. This compound is valuable for research applications investigating mood disorders and serotonergic signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
