Product Data Sheet

Escholtzine

Catalog No. A46095

main product photo
Escholtzine is an alkaloid derived from Eschscholzia californica, primarily known for its inhibitory effects on the 5-HT1A receptor, demonstrated by an EC50 value of 11 μM and a Ki of 6 μM. Additionally, it inhibits CYP3A4 with an IC50 of 13.4 μg/mL. This compound is valuable for research in neurological diseases, particularly in models related to anxiety.
Chemical Information
Catalog NumA46095
M. Wt323.34
FormulaC19H17NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.4040-75-9
Synonyms
SMILES[H][C@]1(N2C)CC3=CC4=C(OCO4)C=C3[C@]2([H])CC5=CC6=C(OCO6)C=C51
Biological Activity
DescriptionEscholtzine is an alkaloid derived from Eschscholzia californica, primarily known for its inhibitory effects on the 5-HT1A receptor, demonstrated by an EC50 value of 11 μM and a Ki of 6 μM. Additionally, it inhibits CYP3A4 with an IC50 of 13.4 μg/mL. This compound is valuable for research in neurological diseases, particularly in models related to anxiety.
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