Product Data Sheet
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
Catalog No. A46131
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC designed to facilitate targeted protein degradation. This compound integrates a p-fluorobenzylguanine (FBnG) tag with a glycol spacer, enabling effective K63-linked polyubiquitination. It demonstrates significant biological activity by promoting the degradation of mitochondrial proteins in HeLa cells, making it a valuable tool for researchers studying mitochondrial dynamics and protein homeostasis.
Chemical Information
| Catalog Num | A46131 |
|---|---|
| M. Wt | 622.71 |
| Formula | C27H39FN8O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2241669-84-9 |
| Synonyms | |
| SMILES | NCCCOCCOCCOCCCNC([C@H](CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NC(C)=O)=O |
Biological Activity
| Description | FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC designed to facilitate targeted protein degradation. This compound integrates a p-fluorobenzylguanine (FBnG) tag with a glycol spacer, enabling effective K63-linked polyubiquitination. It demonstrates significant biological activity by promoting the degradation of mitochondrial proteins in HeLa cells, making it a valuable tool for researchers studying mitochondrial dynamics and protein homeostasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
