Product Data Sheet

Methyl arachidonate

Catalog No. A46253

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Methyl arachidonate is an activator of protein kinase C, functioning as an orally active substrate that is subject to esterase-mediated hydrolysis. It promotes the indirect activation of protein kinase C through the generation of eicosanoid metabolites from the arachidonic acid metabolic pathway, demonstrating differential effects via cyclooxygenase products at low concentrations and lipoxygenase products at elevated concentrations. This compound is valuable for investigations into mechanisms related to lipodystrophy.
Chemical Information
Catalog NumA46253
M. Wt318.49
FormulaC21H34O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2566-89-4
SynonymsArachidonic acid methyl ester
SMILESCCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC)=O
Biological Activity
DescriptionMethyl arachidonate is an activator of protein kinase C, functioning as an orally active substrate that is subject to esterase-mediated hydrolysis. It promotes the indirect activation of protein kinase C through the generation of eicosanoid metabolites from the arachidonic acid metabolic pathway, demonstrating differential effects via cyclooxygenase products at low concentrations and lipoxygenase products at elevated concentrations. This compound is valuable for investigations into mechanisms related to lipodystrophy.
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