Product Data Sheet
Methotrexate hydrate
Catalog No. A46351
Methotrexate hydrate is a potent inhibitor of dihydrofolate reductase, targeting folate metabolism to disrupt DNA synthesis and cellular proliferation. This reagent is widely utilized in biochemical assays, particularly in cancer research and the treatment of autoimmune disorders, to examine cell growth, division, and response to therapy. Its mechanism of action provides a critical tool for investigating cellular processes and therapeutic efficacy in various disease models.
Chemical Information
| Catalog Num | A46351 |
|---|---|
| M. Wt | 472.462 |
| Formula | C20H22N8O5.xH2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 133073-73-1 |
| Synonyms | Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate |
| SMILES | NC1=NC(N)=C2C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=N1.O.[x] |
Biological Activity
| Description | Methotrexate hydrate is a potent inhibitor of dihydrofolate reductase, targeting folate metabolism to disrupt DNA synthesis and cellular proliferation. This reagent is widely utilized in biochemical assays, particularly in cancer research and the treatment of autoimmune disorders, to examine cell growth, division, and response to therapy. Its mechanism of action provides a critical tool for investigating cellular processes and therapeutic efficacy in various disease models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
