Product Data Sheet
Venturicidin A
Catalog No. A46439
Venturicidin A is a macrolide antibiotic that acts as a potent inhibitor of ATP synthase. Derived from actinomycetes, it enhances the efficacy of the aminoglycoside antibiotic gentamicin against multidrug-resistant strains of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Although Venturicidin A demonstrates significant antibacterial activity, it also exhibits notable toxicity towards human embryonic kidney (HEK) cells, with an IC50 value of 31 μg/mL, making it a valuable compound for research in antibiotic resistance and cellular response assessments.
Chemical Information
| Catalog Num | A46439 |
|---|---|
| M. Wt | 749.97 |
| Formula | C41H67NO11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 33538-71-5 |
| Synonyms | Aabomycin A1 |
| SMILES | CC1=CC[C@](O)(C2)O[C@]1([H])/C(C)=C\CCC[C@](O[C@@]3([H])C[C@H]([C@H](O)[C@@H](C)O3)OC(N)=O)([H])/C=C/[C@H](C)C[C@@H](C)[C@]([C@H](C)C[C@@H](C)[C@H](O)[C@H](C)C(CC)=O)([H])OC2=O |
Biological Activity
| Description | Venturicidin A is a macrolide antibiotic that acts as a potent inhibitor of ATP synthase. Derived from actinomycetes, it enhances the efficacy of the aminoglycoside antibiotic gentamicin against multidrug-resistant strains of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Although Venturicidin A demonstrates significant antibacterial activity, it also exhibits notable toxicity towards human embryonic kidney (HEK) cells, with an IC50 value of 31 μg/mL, making it a valuable compound for research in antibiotic resistance and cellular response assessments. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
