Product Data Sheet
Cephalothin
Catalog No. A46455
Cephalothin is a semi-synthetic cephalosporin antibiotic classified as a β-lactam antibiotic. It exerts its antibacterial activity by inhibiting class C β-lactamase AmpC with a Ki of 0.32 µM while also binding to penicillin-binding proteins, thereby disrupting the cross-linking of peptidoglycan in the bacterial cell wall. This mechanism impedes bacterial cell wall synthesis, allowing it to effectively target a broad spectrum of bacteria. Cephalothin is applicable in studies related to hematology and nephrotoxicity.
Chemical Information
| Catalog Num | A46455 |
|---|---|
| M. Wt | 396.44 |
| Formula | C16H16N2O6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153-61-7 |
| Synonyms | Cephalotin |
| SMILES | O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(CC3=CC=CS3)=O)C1=O)O |
Biological Activity
| Description | Cephalothin is a semi-synthetic cephalosporin antibiotic classified as a β-lactam antibiotic. It exerts its antibacterial activity by inhibiting class C β-lactamase AmpC with a Ki of 0.32 µM while also binding to penicillin-binding proteins, thereby disrupting the cross-linking of peptidoglycan in the bacterial cell wall. This mechanism impedes bacterial cell wall synthesis, allowing it to effectively target a broad spectrum of bacteria. Cephalothin is applicable in studies related to hematology and nephrotoxicity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
