Product Data Sheet
Neplanocin A
Catalog No. A46463
Neplanocin A is an antitumor antibiotic that functions as an irreversible inhibitor of AdoHcy hydrolase, with a Ki of 8.39 nM. It exhibits significant antitumor activity against murine L1210 leukemia cells and also demonstrates antiviral properties, notably against the vaccinia virus. This compound is isolated from the marine-derived organism Ampulariella regularis, making it a valuable reagent for research in cancer therapeutics and virology.
Chemical Information
| Catalog Num | A46463 |
|---|---|
| M. Wt | 263.25 |
| Formula | C11H13N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 72877-50-0 |
| Synonyms | (-)-Neplanocin A |
| SMILES | O[C@@H]1[C@H](O)C(CO)=C[C@H]1N2C=NC3=C(N)N=CN=C23 |
Biological Activity
| Description | Neplanocin A is an antitumor antibiotic that functions as an irreversible inhibitor of AdoHcy hydrolase, with a Ki of 8.39 nM. It exhibits significant antitumor activity against murine L1210 leukemia cells and also demonstrates antiviral properties, notably against the vaccinia virus. This compound is isolated from the marine-derived organism Ampulariella regularis, making it a valuable reagent for research in cancer therapeutics and virology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
