Product Data Sheet
Azidamfenicol
Catalog No. A46548
Azidamfenicol is a chloramphenicol-like antibiotic that functions by inhibiting ribosomal peptidyltransferase with a Ki value of 22 μM. This broad-spectrum agent exhibits significant antibacterial activity, making it useful in studying bacterial protein synthesis. Additionally, Azidamfenicol serves as a click chemistry reagent due to the presence of an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. This dual functionality allows for versatile applications in chemical biology and bioconjugation strategies.
Chemical Information
| Catalog Num | A46548 |
|---|---|
| M. Wt | 295.25 |
| Formula | C11H13N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 13838-08-9 |
| Synonyms | |
| SMILES | O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)CN=[N+]=[N-] |
Biological Activity
| Description | Azidamfenicol is a chloramphenicol-like antibiotic that functions by inhibiting ribosomal peptidyltransferase with a Ki value of 22 μM. This broad-spectrum agent exhibits significant antibacterial activity, making it useful in studying bacterial protein synthesis. Additionally, Azidamfenicol serves as a click chemistry reagent due to the presence of an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. This dual functionality allows for versatile applications in chemical biology and bioconjugation strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
