Product Data Sheet
ZG297
Catalog No. A46615
ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. This compound effectively degrades SaFtsZ and inhibits bacterial cell division, demonstrating potent antistaphylococcal activity against S. aureus 8325-4 and MRSA strains, with a minimum inhibitory concentration (MIC) ranging from 0.063 to 256 μg/mL. Additionally, ZG297 has shown efficacy in anti-infectious applications in mouse models, making it a valuable tool for research in antibiotic development.
Chemical Information
| Catalog Num | A46615 |
|---|---|
| M. Wt | 568.63 |
| Formula | C31H35F3N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2999673-52-6 |
| Synonyms | |
| SMILES | FC(F)(F)CCCNC(N1[C@](CN(CC2=CC(C=CC=C3)=C3C4=C2C=CC=C4)C([C@@H]5[C@H](CC)C)=O)([H])N5C(CC1)=O)=O |
Biological Activity
| Description | ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. This compound effectively degrades SaFtsZ and inhibits bacterial cell division, demonstrating potent antistaphylococcal activity against S. aureus 8325-4 and MRSA strains, with a minimum inhibitory concentration (MIC) ranging from 0.063 to 256 μg/mL. Additionally, ZG297 has shown efficacy in anti-infectious applications in mouse models, making it a valuable tool for research in antibiotic development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
