Product Data Sheet
IMipenem and cilastatin sodium
Catalog No. A46630
Imipenem and cilastatin sodium is a broad-spectrum carbapenem antibiotic combination effective against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem, the active antibiotic, exhibits rapid bactericidal activity, while cilastatin acts as a renal dehydropeptidase inhibitor, preventing the renal metabolism of imipenem and enhancing its urinary concentration. This combination is commonly utilized in research settings to study antibiotic efficacy and resistance mechanisms.
Chemical Information
| Catalog Num | A46630 |
|---|---|
| M. Wt | 679.78 |
| Formula | C28H42N5NaO9S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85960-17-4 |
| Synonyms | |
| SMILES | C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(C(O)=O)N2C1=O.CC3(C)C[C@@H]3C(N/C(C([O-])=O)=C\CCCCSC[C@H](N)C(O)=O)=O.[Na+] |
Biological Activity
| Description | Imipenem and cilastatin sodium is a broad-spectrum carbapenem antibiotic combination effective against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem, the active antibiotic, exhibits rapid bactericidal activity, while cilastatin acts as a renal dehydropeptidase inhibitor, preventing the renal metabolism of imipenem and enhancing its urinary concentration. This combination is commonly utilized in research settings to study antibiotic efficacy and resistance mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
