Gatifloxacin sesquihydrate
Catalog No. A46696

Gatifloxacin sesquihydrate is a potent fluoroquinolone antibiotic that primarily targets bacterial type II topoisomerases. It exhibits broad-spectrum antibacterial activity, demonstrating significant inhibition of S. aureus topoisomerase IV and E. coli DNA gyrase with IC50 values of 13.8 μg/ml and 0.109 μg/ml, respectively. This compound is particularly useful in research related to bacterial infections and may serve as a therapeutic agent for conditions such as bacterial conjunctivitis.
Chemical Information
| Catalog Num | A46696 |
|---|---|
| M. Wt | 402.43 |
| Formula | C19H22FN3O4.3/2H2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 180200-66-2 |
| Synonyms | AM-1155 sesquihydrate; BMS-206584 sesquihydrate; PD135432 sesquihydrate |
| SMILES | [H]O[H].O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(C)NCC4)=C3OC)C1=O)O.[3/2] |
Biological Activity
| Description | Gatifloxacin sesquihydrate is a potent fluoroquinolone antibiotic that primarily targets bacterial type II topoisomerases. It exhibits broad-spectrum antibacterial activity, demonstrating significant inhibition of S. aureus topoisomerase IV and E. coli DNA gyrase with IC50 values of 13.8 μg/ml and 0.109 μg/ml, respectively. This compound is particularly useful in research related to bacterial infections and may serve as a therapeutic agent for conditions such as bacterial conjunctivitis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


