Product Data Sheet
DC-756
Catalog No. A46771
DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies.
Chemical Information
| Catalog Num | A46771 |
|---|---|
| M. Wt | 393.38 |
| Formula | C19H21F2N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 218281-25-5 |
| Synonyms | |
| SMILES | COC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4C[C@@H]([C@@H](C4)N)CF)=O)C(O)=O |
Biological Activity
| Description | DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
