Product Data Sheet
Terrecyclic Acid
Catalog No. A46803
Terrecyclic Acid is a sesquiterpene derived from the fungal species Aspergillus terreus. This compound exhibits notable antibiotic and anticancer properties, demonstrating activity against Staphylococcus aureus, Bacillus subtilis, and Micromonospora roseus with minimum inhibitory concentrations of 25, 50, and 25 μg/mL, respectively. Additionally, terrecyclic acid induces a heat shock response, elevates reactive oxygen species (ROS) levels, and suppresses NF-κB activity and cellular proliferation in 3T3-Y9-B12 cells. In vivo studies reveal that terrecyclic acid effectively reduces ascitic fluid tumor cell counts in a mouse model of P388 murine leukemia at concentrations of 0.1, 1, and 10 mg/mL.
Chemical Information
| Catalog Num | A46803 |
|---|---|
| M. Wt | 248.32 |
| Formula | C15H20O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 83058-94-0 |
| Synonyms | |
| SMILES | OC([C@H](CC1)[C@@](C2)(C3=C)[C@@](CC3=O)([H])[C@]1([H])C2(C)C)=O |
Biological Activity
| Description | Terrecyclic Acid is a sesquiterpene derived from the fungal species Aspergillus terreus. This compound exhibits notable antibiotic and anticancer properties, demonstrating activity against Staphylococcus aureus, Bacillus subtilis, and Micromonospora roseus with minimum inhibitory concentrations of 25, 50, and 25 μg/mL, respectively. Additionally, terrecyclic acid induces a heat shock response, elevates reactive oxygen species (ROS) levels, and suppresses NF-κB activity and cellular proliferation in 3T3-Y9-B12 cells. In vivo studies reveal that terrecyclic acid effectively reduces ascitic fluid tumor cell counts in a mouse model of P388 murine leukemia at concentrations of 0.1, 1, and 10 mg/mL. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
