Product Data Sheet
Medermycin
Catalog No. A46833
Medermycin is an antitumor antibiotic that primarily exerts its effects through inhibition of various cancer cell lines. It demonstrates potent activity against lymphoma L5178Y progenitor cells and multiple drug-resistant leukemias, with ID50 values of 0.02 μg/mL for L5178Y, 0.006 μg/mL for Adriamycin-resistant cells, and 0.008 μg/mL for Bleomycin-resistant cells, among others. Medermycin is valuable for research applications focused on cancer treatment and the mechanisms of antibiotic resistance.
Chemical Information
| Catalog Num | A46833 |
|---|---|
| M. Wt | 457.47 |
| Formula | C24H27NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 60227-09-0 |
| Synonyms | Lactoquinomycin A; LQM-A |
| SMILES | O=C1C2=C(C(C3=C(O)C([C@H]4C[C@H]([C@@H]([C@H](O4)C)O)N(C)C)=CC=C31)=O)[C@@H](C)O[C@@](C5)([H])[C@]2([H])OC5=O |
Biological Activity
| Description | Medermycin is an antitumor antibiotic that primarily exerts its effects through inhibition of various cancer cell lines. It demonstrates potent activity against lymphoma L5178Y progenitor cells and multiple drug-resistant leukemias, with ID50 values of 0.02 μg/mL for L5178Y, 0.006 μg/mL for Adriamycin-resistant cells, and 0.008 μg/mL for Bleomycin-resistant cells, among others. Medermycin is valuable for research applications focused on cancer treatment and the mechanisms of antibiotic resistance. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
