Product Data Sheet
LY164846
Catalog No. A46944
LY164846 is an orally active cephalosporin antibiotic that primarily targets Haemophilus influenzae, exhibiting high sensitivity to both typical and ampicillin-resistant strains, with an MIC90 ≤ 4 μg/mL. The compound also demonstrates significant activity against Methicillin-resistant Staphylococcus aureus and Streptococcus species (excluding Enterococcus), with MIC90 values ranging from 0.25 to 8 μg/mL, and shows moderate sensitivity towards anaerobic bacteria. Its bactericidal properties are indicated by an MBC/MIC ratio of ≤ 2 against Haemophilus influenzae. LY164846 is valuable for investigating respiratory and skin infections in biomedical research.
Chemical Information
| Catalog Num | A46944 |
|---|---|
| M. Wt | 403.48 |
| Formula | C18H17N3O4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 92218-37-6 |
| Synonyms | |
| SMILES | O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CSC4=CC=CC=C43)=O)C1=O)O |
Biological Activity
| Description | LY164846 is an orally active cephalosporin antibiotic that primarily targets Haemophilus influenzae, exhibiting high sensitivity to both typical and ampicillin-resistant strains, with an MIC90 ≤ 4 μg/mL. The compound also demonstrates significant activity against Methicillin-resistant Staphylococcus aureus and Streptococcus species (excluding Enterococcus), with MIC90 values ranging from 0.25 to 8 μg/mL, and shows moderate sensitivity towards anaerobic bacteria. Its bactericidal properties are indicated by an MBC/MIC ratio of ≤ 2 against Haemophilus influenzae. LY164846 is valuable for investigating respiratory and skin infections in biomedical research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
