Product Data Sheet
Clindamycin Sulfoxide
Catalog No. A47040
Clindamycin Sulfoxide is an active metabolite of the antibiotic clindamycin, primarily generated through S-oxidation via the cytochrome P450 isoform CYP3A4. This compound exhibits significant antibacterial activity, effectively inhibiting the growth of anaerobic bacteria, including Peptostreptococcus prevotti, Bacteroides fragilis, and Clostridium sordelli, with minimal inhibitory concentration (MIC) values of 2 mg/L, 2 mg/L, and 1 mg/L, respectively. Clindamycin sulfoxide serves as a valuable tool for research applications focused on antibiotic efficacy and resistance mechanisms.
Chemical Information
| Catalog Num | A47040 |
|---|---|
| M. Wt | 440.98 |
| Formula | C18H33ClN2O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 22431-46-5 |
| Synonyms | U-25026A |
| SMILES | O=C([C@H]1N(C[C@@H](C1)CCC)C)N[C@@]([H])([C@]2(O[C@@]([H])([C@@H]([C@H]([C@H]2O)O)O)S(C)=O)[H])[C@@H](Cl)C |
Biological Activity
| Description | Clindamycin Sulfoxide is an active metabolite of the antibiotic clindamycin, primarily generated through S-oxidation via the cytochrome P450 isoform CYP3A4. This compound exhibits significant antibacterial activity, effectively inhibiting the growth of anaerobic bacteria, including Peptostreptococcus prevotti, Bacteroides fragilis, and Clostridium sordelli, with minimal inhibitory concentration (MIC) values of 2 mg/L, 2 mg/L, and 1 mg/L, respectively. Clindamycin sulfoxide serves as a valuable tool for research applications focused on antibiotic efficacy and resistance mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
