Product Data Sheet

Clindamycin phosphate hydrochloride

Catalog No. A47141

main product photo
Clindamycin phosphate hydrochloride is a prodrug of the lincosamide antibiotic clindamycin, which exerts its bacteriostatic activity by inhibiting bacterial protein synthesis. Although Clindamycin phosphate itself lacks in vitro antimicrobial properties, it is rapidly metabolized to active clindamycin in vivo via phosphatase ester hydrolysis. This reagent is valuable for research applications involving acne treatment and bacterial vaginosis, facilitating studies on antibiotic efficacy and resistance mechanisms.
Chemical Information
Catalog NumA47141
M. Wt541.42
FormulaC18H35Cl2N2O8PS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.64023-51-4
SynonymsClindamycin 2-phosphate hydrochloride; U-28508 hydrochloride
SMILESCCC[C@H]1CN(C)[C@H](C(N[C@@]([H])([C@@]2([H])O[C@H](SC)[C@H](OP(O)(O)=O)[C@@H](O)[C@H]2O)[C@@H](Cl)C)=O)C1.[H]Cl
Biological Activity
DescriptionClindamycin phosphate hydrochloride is a prodrug of the lincosamide antibiotic clindamycin, which exerts its bacteriostatic activity by inhibiting bacterial protein synthesis. Although Clindamycin phosphate itself lacks in vitro antimicrobial properties, it is rapidly metabolized to active clindamycin in vivo via phosphatase ester hydrolysis. This reagent is valuable for research applications involving acne treatment and bacterial vaginosis, facilitating studies on antibiotic efficacy and resistance mechanisms.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.