Product Data Sheet
CK0492B
Catalog No. A47192
CK0492B is a novel biaminourea antibiotic that targets bacterial plaque formation. Demonstrating significant antiplaque properties in vitro, it has also shown efficacy in reducing dental disease symptoms in an experimental mouse model. A 12-week study conducted in beagles highlighted its effectiveness in decreasing plaque and gingivitis while assessing its safety profile. The selection of canine subjects is informed by the similarities in periodontal disease onset and progression between dogs and humans, with chlorhexidine acetate serving as a positive control for comparison.
Chemical Information
| Catalog Num | A47192 |
|---|---|
| M. Wt | 831.10 |
| Formula | C36H66N10O8S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 64169-11-5 |
| Synonyms | |
| SMILES | O=C(NC12CC3CC(C2)CC(C1)C3)NC(NCCCN4CCN(CCCNC(NC(NC56CC7CC(C6)CC(C5)C7)=O)=N)CC4)=N.O=S(O)(C)=O.O=S(O)(C)=O |
Biological Activity
| Description | CK0492B is a novel biaminourea antibiotic that targets bacterial plaque formation. Demonstrating significant antiplaque properties in vitro, it has also shown efficacy in reducing dental disease symptoms in an experimental mouse model. A 12-week study conducted in beagles highlighted its effectiveness in decreasing plaque and gingivitis while assessing its safety profile. The selection of canine subjects is informed by the similarities in periodontal disease onset and progression between dogs and humans, with chlorhexidine acetate serving as a positive control for comparison. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
