Product Data Sheet
Clavicoronic acid
Catalog No. A47225
Clavicoronic acid is an inhibitor of reverse transcriptases from avian myeloblastosis virus and Moloney murine leukemia virus, exhibiting Ki values of 130 µM and 68 µM, respectively. This compound effectively inhibits the replication of vesicular stomatitis virus by disrupting its RNA-directed RNA polymerase activity. Notably, Clavicoronic acid demonstrates no cytotoxic effects, making it a valuable tool for research applications focused on viral replication mechanisms and antiviral drug development.
Chemical Information
| Catalog Num | A47225 |
|---|---|
| M. Wt | 262.30 |
| Formula | C15H18O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 139748-98-4 |
| Synonyms | |
| SMILES | CC1=C(C(C(O)=O)=O)C(C=O)=C[C@@]2([H])[C@]1([H])CC(C)(C)C2 |
Biological Activity
| Description | Clavicoronic acid is an inhibitor of reverse transcriptases from avian myeloblastosis virus and Moloney murine leukemia virus, exhibiting Ki values of 130 µM and 68 µM, respectively. This compound effectively inhibits the replication of vesicular stomatitis virus by disrupting its RNA-directed RNA polymerase activity. Notably, Clavicoronic acid demonstrates no cytotoxic effects, making it a valuable tool for research applications focused on viral replication mechanisms and antiviral drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
