Product Data Sheet
Plazomicin
Catalog No. A47246
Plazomicin is a semi-synthetic aminoglycoside antibiotic that targets bacterial ribosomes by inhibiting protein synthesis. It serves as a substrate for aminoglycoside acetyltransferase and aminoglycoside phosphotransferase, yet remains resistant to common aminoglycoside-modifying enzymes. Plazomicin selectively inhibits MATE2-K and demonstrates significant activity against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales, making it valuable for research in antibiotic resistance and treatment efficacy studies.
Chemical Information
| Catalog Num | A47246 |
|---|---|
| M. Wt | 592.68 |
| Formula | C25H48N6O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1154757-24-0 |
| Synonyms | ACHN 490 |
| SMILES | O[C@H]([C@H]([C@@](C)(O)CO1)NC)[C@@]1([H])O[C@H]2[C@@H](C[C@H](N)[C@@H](O[C@@]3([H])OC(CNCCO)=CC[C@H]3N)[C@@H]2O)NC([C@@H](O)CCN)=O |
Biological Activity
| Description | Plazomicin is a semi-synthetic aminoglycoside antibiotic that targets bacterial ribosomes by inhibiting protein synthesis. It serves as a substrate for aminoglycoside acetyltransferase and aminoglycoside phosphotransferase, yet remains resistant to common aminoglycoside-modifying enzymes. Plazomicin selectively inhibits MATE2-K and demonstrates significant activity against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales, making it valuable for research in antibiotic resistance and treatment efficacy studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
